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KMID : 1094020150320040352
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Journal of Veterinary Clinics
2015 Volume.32 No. 4 p.352 ~ p.355
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Preservation through Cloning of Superior Canine Scent Detection Ability for Cancer Screening
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Kim Min-Jung
Park Jung-Eun
Oh Hyun-Ju
Lee Byeong-Chun
Hong So-Gun
Kang Jung-Taek
Rhim Sang-Hyun
Lee Dong-Won
Ra Jung-Chan
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Abstract
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This study was conducted to ascertain whether the scent detection ability of a donor dog having extraordinary talent in cancer detection can be conserved through cloning. A specially trained dog for colorectal cancer detection was cloned, and she was trained and tested to detect breast cancers using breath samples collected from patients and healthy volunteers. Scent detection sensitivity of the clone was 93.3% and specificity was 99.5%, similar with those of donor (91% and 99%). Furthermore, the clone successfully detected early stage of breast cancers. Therefore, superior canine scent detection ability for cancer screening could be preserved through cloning.
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KEYWORD
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canine scent detection, cloning, dogs, breast cancers, diagnosis
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